Protein Engineering Design and Selection

ORIGINAL ARTICLES:

Klaus Hornischer and Helmut Blöcker

Grafting of discontinuous sites: a protein modeling strategy
Protein Eng. 1996 9: 931-939; doi:10.1093/protein/9.11.931 [Abstract] [PDF] [Request Permissions]  

David J. Thomas, Georg Casari, and Chris Sander

The prediction of protein contacts from multiple sequence alignments
Protein Eng. 1996 9: 941-948; doi:10.1093/protein/9.11.941 [Abstract] [PDF] [Request Permissions]  

Louis Patard, Véronique Stoven, Bouchra Gharib, François Bontems, Jean-Yves Lallemand, and Max De Reggi

What function for human lithostathine?: structural investigations by three-dimensional structure modeling and high-resolution NMR spectroscopy
Protein Eng. 1996 9: 949-957; doi:10.1093/protein/9.11.949 [Abstract] [PDF] [Request Permissions]  

Abdelaziz Yasri, Laurent Chiche, Jacques Haiech, and Gerard Grassy

Rational choice of molecular dynamics simulation parameters through the use of the three-dimensional autocorrelation method: application to calmodulin flexibility study
Protein Eng. 1996 9: 959-976; doi:10.1093/protein/9.11.959 [Abstract] [PDF] [Request Permissions]  

Ming-Hsiang Feng, Shek Ling Chan, Yuefang Xiang, Carol P. Huber, and Carmay Lim

The binding mode of an E-64 analog to the active site of cathepsin B
Protein Eng. 1996 9: 977-986; doi:10.1093/protein/9.11.977 [Abstract] [PDF] [Request Permissions]  

Thierry Moreau and Francis Gauthier

Homology modelling of rat kallikrein rK9, a member of the tissue kallikrein family: implications for substrate specificity and inhibitor binding
Protein Eng. 1996 9: 987-995; doi:10.1093/protein/9.11.987 [Abstract] [PDF] [Request Permissions]  

Péter Bagossi, Yin-Shyun E. Cheng, Stephen Oroszlan, and József Tözsér

Activity of linked HIV-1 proteinase dimers containing mutations in the active site region
Protein Eng. 1996 9: 997-1003; doi:10.1093/protein/9.11.997 [Abstract] [PDF] [Request Permissions]  

Thomas Lanio, Ursel Selent, Christian Wenz, Wolfgang Wende, Alexandra Schulz, M. Adiraj, Seturam B. Katti, and Alfred Pingoud

EcoRV-T94V: a mutant restriction endonuclease with an altered substrate specificity towards modified oligodexynucleotides
Protein Eng. 1996 9: 1005-1010; doi:10.1093/protein/9.11.1005 [Abstract] [PDF] [Request Permissions]  

Raj Gill, Brenda Wallach, Chandra Verma, Birgitte Ursø, Elke De Wolf, Joachim Grötzinger, Judith Murray-Rust, Jim Pitts, Axel Wollmer, Pierre De Meyts, and Steve Wood

Engineering the C-region of human insulin-like growth factor-1: implications for receptor binding
Protein Eng. 1996 9: 1011-1019; doi:10.1093/protein/9.11.1011 [Abstract] [PDF] [Request Permissions]  

Paul J.L. Werten, John A. Carver, Rainer Jaenicke, and Wilfried W. de Jong

The elusive role of the N-terminal extension of ßA3- and ßAl-crystallin
Protein Eng. 1996 9: 1021-1028; doi:10.1093/protein/9.11.1021 [Abstract] [PDF] [Request Permissions]  

Brian Tripet, Lei Yu, Daisy L. Bautista, Wah Y. Wong, Randall T. Irvin, and Robert S. Hodges

Engineering a de novo-designed coiled-coil heterodimerization domain for the rapid detection, purification and characterization of recombinantly expressed peptides and proteins
Protein Eng. 1996 9: 1029-1042; doi:10.1093/protein/9.11.1029 [Abstract] [PDF] [Request Permissions]  

Helen L. Parsons, John C. Earnshaw, Jane Wilton, Kevin S. Johnson, Paula A. Schueler, Walt Mahoney, and John McCafferty

Directing phage selections towards specific epitopes
Protein Eng. 1996 9: 1043-1049; doi:10.1093/protein/9.11.1043 [Abstract] [PDF] [Request Permissions]  

Per-Johan Meijer, Niklas Holmberg, Gunilla Grundström, and Leif Bülow

Directed evolution of a type I antifreeze protein expressed in Escherichia coli with sodium chloride as selective pressure and its effect on antifreeze tolerance
Protein Eng. 1996 9: 1051-1054; doi:10.1093/protein/9.11.1051 [Abstract] [PDF] [Request Permissions]  

Manoj K. Ramjee, Joanne R. Petithory, John McElver, Shane C. Weber, and Jack F. Kirsch

A novel yeast expression/secretion system for the recombinant plant thiol endoprotease propapain
Protein Eng. 1996 9: 1055-1061; doi:10.1093/protein/9.11.1055 [Abstract] [PDF] [Request Permissions]  

PROTOCOL:

Lawrence A. Kelley, Stephen P. Gardner, and Michael J. Sutcliffe

An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies
Protein Eng. 1996 9: 1063-1065; doi:10.1093/protein/9.11.1063 [PDF] [Request Permissions]  

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